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Azithromycin is an antibiotic useful for the treatment of a number of bacterial infections. Common side effects include nausea, vomiting, diarrhea and upset stomach. Azithromycin was first discovered in 1980. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. 33 for a course of treatment.
Prevention and treatment of acute bacterial exacerbations of chronic obstructive pulmonary disease due to H. The benefits of long-term prophylaxis must be weighed on a patient-by-patient basis against the risk of cardiovascular and other adverse effects. Acute bacterial sinusitis due to H. Acute otitis media caused by H. Azithromycin is not, however, a first-line agent for this condition.
Amoxicillin or another beta lactam antibiotic is generally preferred. Pharyngitis or tonsillitis caused by S. Uncomplicated skin and skin structure infections due to S. Urethritis and cervicitis due to C.
In combination with ceftriaxone, azithromycin is part of the United States Centers for Disease Control-recommended regimen for the treatment of gonorrhea. Azithromycin has relatively broad but shallow antibacterial activity. It inhibits some Gram-positive bacteria, some Gram-negative bacteria, and many atypical bacteria. A strain of gonorrhea reported to be highly resistant to azithromycin was found in the population in 2015. Neisseria gonorrhoeae is normally susceptible to azithromycin, but the drug is not widely used as monotherapy due to a low barrier to resistance development.
No harm has been found with use during pregnancy. However, there are no adequate well-controlled studies in pregnant women. Safety of the medication during breastfeeding is unclear. It has been reported that because only low levels are found in breastmilk and the medication has also been used in young children, it is unlikely that breastfed infants would suffer adverse effects. Nevertheless, it is recommended that the drug be used with caution during breastfeeding. Nervousness, dermatologic reactions, and anaphylaxis have been reported. Occasionally, patients have developed cholestatic hepatitis or delirium.